Structural Biology What is the phase problem

300618VO + SE Structural Biology I (Macromolecular Crystallography) (2010S)

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Next lecture will be on Wednesday 10th March at 9: 30h Lectures will be every Monday and Wednesday at 9: 30h Lectures will be in Lecture Hall A, Dept. for Structural and Computational Biology
Campus Vienna Biocenter 5
http://www.univie.ac.at/biolchem/location.html Lecture notes can be downloaded from:
https://download.yousendit.com/S1VDNU1LU1BGOFJMWEE9PQ

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information

Objectives, content and method of the course

Lecture notes can be downloaded from:
https://download.yousendit.com/S1VDNU1LU1BGOFJMWEE9PQ The following topics will be covered:
* sources of X-rays
* crystallization techniques
* symmetry (point groups, space groups), unit cell, Bravais lattice
* scattering of X-rays, atomic form factor, structure factor
* waves, diffraction of molecules and crystals, Fourier transform; electron density
* set-up of MX diffraction experiment and detectors
* Methods for solution of phase problem: molecular replacement, multiple isomorphous replacement, multi-wavelength anomalous dispersion
* density modification techniques
* structure refinement and analysis.

Type of performance control and permitted aids

Schedule for oral exams in Structural Biology I 21.4. 2010: Location: Department for Structural and Computational Biology,
Room 160614: 00 Handlos, Judith, 0645096
14:30 Bauer, Moritz, 0700941
15:00 Granofszky, Nicolas, 0701708
3:30 p.m. Lackner, Andreas, 9908277
16:00 Mattes, Katharina, 0708450
17:30 Mayr, Julia, 0555036
18:00 Sieghart, Fabian, 0608982
18:30 Taubenschmid, Jasmin, 0700522
19:00 Zadnikar, Rene, 070517115: 00
15:30
16:00
16:30
17:00
17:30
18:00

Minimum requirements and assessment criteria

Examination material

literature


Assignment in the course catalog

Last change: Wed 19.08.2020 08:08